What files can be deleted or moved from the c: drive on the core server to another drive on the core Server?

I am needing to move or delete files from my LDMS 9.5 SP1 server C:\ drive.  What can be safely deleted and what can be moved to another drive on the core server (Win 2K8 R2)?  I am running into space issues and need to check what LANDesk files and services can be moved to another drive. LDMS was installed onto the E:\ of the server.

Thanks.